PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22743997-1 2012 Unlike other serine proteases that are zymogens, the single-chain form of tissue plasminogen activator (sc-tPA) exhibits an intrinsic activity similar to that of its cleaved two-chain form (tc-tPA), especially in the presence of fibrin. tc-tpa 190-196 chromosome 20 open reading frame 181 Homo sapiens 74-102