PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9276494-10 1997 The N-methyl-D-aspartate-type receptor antagonist, dizocilpine, at 0.1-0.5 mg/kg i.p., produced a marked and persistent reduction in striatal glutamate decarboxylase 67 messenger RNA. Dizocilpine Maleate 51-62 glutamate-ammonia ligase Rattus norvegicus 142-165 8547590-1 1995 Levels of mRNAs encoding for the two isoforms of glutamate decarboxylase, GAD67 and GAD65, were quantified in the rat striatum and cerebral cortex following single injections of the non-competitive NMDA receptor antagonist MK-801. Dizocilpine Maleate 223-229 glutamate-ammonia ligase Rattus norvegicus 49-72 1680225-6 1991 Administration of dizocilpine at 1, 2, 3 or 5 h after injection of 100, 200 or 400 nmol quinolinate resulted in a similar temporal profile of neuroprotection, as assessed by measuring the activities of choline acetyltransferase and glutamate decarboxylase in striatal homogenates, which was independent of the degree of neurodegeneration produced by the different excitotoxin doses. Dizocilpine Maleate 18-29 glutamate-ammonia ligase Rattus norvegicus 232-255 12373737-1 2002 This study examined the consequences of systemic treatment with either L-dopa or MK-801 on the levels of mRNAs encoding the 65 and 67 kDa isoforms of glutamate decarboxylase (GAD65 and GAD67) in the striatum and globus pallidus (GP) of rats rendered hemiparkinsonian by intranigral 6-hydroxydopamine injection. Dizocilpine Maleate 81-87 glutamate-ammonia ligase Rattus norvegicus 150-173