PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10772708-3 2000 Formation of the intramolecular pyrophosphate linkage by a conformation-restriction strategy in a syn-form using a halogen substitution at the 8-position of the adenine ring. diphosphoric acid 32-45 synemin Homo sapiens 98-101 17142283-4 2007 The 3",5"-pyrophosphate group of this compound increases its affinity and introduces structural features which seem to be unique in pyrophosphate-containing ligands bound to RNase A, such as the adoption of a syn conformation by the adenosine base at RNase subsite B(2) and the placement of the 5"-beta-phosphate of the adenylate (instead of the alpha-phosphate) at subsite P(1) where the phosphodiester bond cleavage occurs. diphosphoric acid 10-23 synemin Homo sapiens 209-212 12465899-0 2002 Template-assisted preferential formation of a syn photodimer in a pyrophosphate-induced self-assembly of a thymine-functionalized isothiouronium receptor. diphosphoric acid 66-79 synemin Homo sapiens 46-49 12465899-3 2002 As compared to the case of a free receptor, the presence of pyrophosphate (PPi) resulted in the preferential formation of the syn-type photodimer, which would be desirable for recognizing the templated PPi. diphosphoric acid 60-73 synemin Homo sapiens 126-129