PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2201313-1 1990 We report the synthesis and biological evaluation of a two-chain, disulfide-linked, insulin-like compound consisting of the B-chain of bovine insulin and an A-chain corresponding to the A- and D- domains of human insulin-like growth factor-I (IGF-I) in which the A-domain amino-acid residues -Phe49-Arg50-Ser51-found in IGF-I have been replaced by -Ala-Gly-Val-, the homologous region of sheep insulin. alanylglycine 349-356 insulin like growth factor 1 Homo sapiens 213-241