PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22624680-9 2012 CONCLUSIONS AND IMPLICATIONS: NA-5HT increases the steady-state inactivation of Ca(V) 3 channels, reducing the number of channels available to open during depolarization. na-5ht 30-36 carbonic anhydrase 5A Homo sapiens 80-85 22624680-6 2012 KEY RESULTS: NA-5HT completely inhibited Ca(V) 3 channels with a rank order of potency (pEC(50) ) of Ca(V) 3.1 (7.4) > Ca(V) 3.3 (6.8) >= Ca(V) 3.2 (6.6). na-5ht 13-19 carbonic anhydrase 5A Homo sapiens 41-46 22624680-6 2012 KEY RESULTS: NA-5HT completely inhibited Ca(V) 3 channels with a rank order of potency (pEC(50) ) of Ca(V) 3.1 (7.4) > Ca(V) 3.3 (6.8) >= Ca(V) 3.2 (6.6). na-5ht 13-19 carbonic anhydrase 5A Homo sapiens 101-106 22624680-7 2012 The effects of NA-5HT were voltage-dependent, and it produced significant hyperpolarizing shifts in Ca(V) 3 steady-state inactivation relationships. na-5ht 15-21 carbonic anhydrase 5A Homo sapiens 100-105 22624680-8 2012 NA-5HT selectively affected Ca(V) 3.3 channel kinetics. na-5ht 0-6 carbonic anhydrase 5A Homo sapiens 28-33