PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31521619-3	2019	The aim of the present study is to investigate the neuroprotective effects of gamma-oryzanol (Orz) and elucidate its relevant molecular mechanisms in mutant hSOD1-linked Drosophila and cell models of ALS.	gamma-oryzanol	78-92	superoxide dismutase 1	Homo sapiens	157-162	
31521619-4	2019	Orz treatment provided neuroprotection in flies with expression of hSOD1-G85R in motor neurons, as demonstrated by the prolonged survival, improvement of motor deficits, reduced oxidative damage and regulated redox homeostasis when compared with those in controls.	gamma-oryzanol	0-3	superoxide dismutase 1	Homo sapiens	67-72	
31521619-5	2019	Moreover, Orz significantly decreased neuronal apoptosis and upregulated the nuclear factor erythroid 2-related factor 2 (Nrf2)/glutamate-cysteine ligase catalytic subunit (GCLC) antioxidant pathway via activating Akt in hSOD1-G93A-expressing NSC-34 cells.	gamma-oryzanol	10-13	superoxide dismutase 1	Homo sapiens	221-226