PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29725495-0 2018 Characterization of the Antioxidant Effects of gamma-Oryzanol: Involvement of the Nrf2 Pathway. gamma-oryzanol 47-61 NFE2 like bZIP transcription factor 2 Homo sapiens 82-86 35218032-0 2022 Gamma-oryzanol protects human liver cell (L02) from hydrogen peroxide-induced oxidative damage through regulation of the MAPK/Nrf2 signaling pathways. gamma-oryzanol 0-14 NFE2 like bZIP transcription factor 2 Homo sapiens 126-130 35218032-6 2022 Furthermore, preincubation with Orz reduced H2 O2 -mediated the proapoptotic protein of Bak expression and the phosphorylation of ASK1, p38, JNK, and ERK, and increased the anti-apoptotic protein of Bcl-xl expression and anti-oxidative stress proteins of Nrf2 and HO-1 expression. gamma-oryzanol 32-35 NFE2 like bZIP transcription factor 2 Homo sapiens 255-259 35218032-7 2022 The findings suggested that Orz exerts the cytoprotective effects in H2 O2 -induced L02 cells apoptosis by ameliorating oxidative stress via inhibiting MAPK signaling pathway and activating Nrf2 signaling pathway. gamma-oryzanol 28-31 NFE2 like bZIP transcription factor 2 Homo sapiens 190-194 35218032-9 2022 In this study, it was found that Orz exerts the cytoprotective effects in H2 O2 -induced L02 cell apoptosis by ameliorating oxidative stress via the inhibition of MAPK signaling pathway and the activation of Nrf2 signaling pathway, which provides a theoretical basis for dietary adding natural products to prevent or treat oxidative stress-related diseases. gamma-oryzanol 33-36 NFE2 like bZIP transcription factor 2 Homo sapiens 208-212