PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8376804-7 1993 Aphidicolin inhibited repair and consistently sensitized to TNF cytotoxicity, decreasing the ID50 for TNF at least 10- to 50-fold. Aphidicolin 0-11 tumor necrosis factor Homo sapiens 60-63 8376804-7 1993 Aphidicolin inhibited repair and consistently sensitized to TNF cytotoxicity, decreasing the ID50 for TNF at least 10- to 50-fold. Aphidicolin 0-11 tumor necrosis factor Homo sapiens 102-105 8376804-10 1993 In targets sensitized with aphidicolin, TNF-induced strand breakage was accelerated, being detected by 4 h of culture in the sucrose gradient assay. Aphidicolin 27-38 tumor necrosis factor Homo sapiens 40-43 10880232-4 2000 Cytogenetic analysis showed that, in the presence of aphidicolin, which blocks several types of DNA repair, TNF induced extensive chromosomal damage. Aphidicolin 53-64 tumor necrosis factor Homo sapiens 108-111 10880232-5 2000 Aphidicolin also synergized with TNF and anti-Fas in inducing cell death which was prevented by reducing atmospheric oxygen or addition of n -acetyl cysteine, a scavenger of oxygen radicals. Aphidicolin 0-11 tumor necrosis factor Homo sapiens 33-36 7629160-3 1995 Based on growth arrest experiments using aphidicolin, it is apparent that TNF-alpha acted in early G1 phase. Aphidicolin 41-52 tumor necrosis factor Homo sapiens 74-83