PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29788478-9 2018 However, FANCJ-R707C expressed in fancj-/- cells conferred resistance to the DNA polymerase inhibitor aphidicolin, G-quadruplex ligand telomestatin, or DNA strand-breaker bleomycin, whereas FANCJ-H396D failed. Aphidicolin 102-113 BRCA1 interacting helicase 1 Homo sapiens 9-14 29788478-9 2018 However, FANCJ-R707C expressed in fancj-/- cells conferred resistance to the DNA polymerase inhibitor aphidicolin, G-quadruplex ligand telomestatin, or DNA strand-breaker bleomycin, whereas FANCJ-H396D failed. Aphidicolin 102-113 BRCA1 interacting helicase 1 Homo sapiens 34-39 29788478-10 2018 Thus, a minimal threshold of FANCJ catalytic activity is required to overcome replication stress induced by aphidicolin or telomestatin, or to repair bleomycin-induced DNA breakage. Aphidicolin 108-119 BRCA1 interacting helicase 1 Homo sapiens 29-34 27179029-4 2016 In FANCJ helicase depleted cells, we show that hydroxyurea or aphidicolin treatment leads to loss of microsatellite polymerase chain reaction signals and to chromosome recombination at an ectopic hairpin forming CTG/CAG repeat in the HeLa genome. Aphidicolin 62-73 BRCA1 interacting helicase 1 Homo sapiens 3-8