PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22934511-10 2012 CONCLUSION: Prenatal exposure to diethylstilbestrol affected the expression of LGR8 mRNA in the mouse gubernaculum testis, which suggests that diethylstilbestrol may induce cryptorchidism by interfering with the INSL3-LGR8 signaling system and consequently the development of the gubernaculum testis. Diethylstilbestrol 33-51 relaxin/insulin-like family peptide receptor 2 Mus musculus 218-222 26855023-0 2016 Diethylstilbestrol Regulates the Expression of LGR8 in Mouse Gubernaculum Testis Cells. Diethylstilbestrol 0-18 relaxin/insulin-like family peptide receptor 2 Mus musculus 47-51 26855023-11 2016 CONCLUSIONS These results suggest that DES causes testicular maldescent by altering the LGR8 pathway in mouse gubernaculum testis cells. Diethylstilbestrol 39-42 relaxin/insulin-like family peptide receptor 2 Mus musculus 88-92 32774729-0 2020 RXFP2 as novel potential biomarker for abnormal differentiation induced by diethylstilbestrol in the gubernaculum of fetal mice. Diethylstilbestrol 75-93 relaxin/insulin-like family peptide receptor 2 Mus musculus 0-5 32774729-3 2020 In vitro and in vivo experiments were performed to examine the expression level and mechanism of relaxin family peptide receptor 2 (RXFP2) in the gubernaculum of fetal mice following diethylstilbestrol (DES) treatment. Diethylstilbestrol 183-201 relaxin/insulin-like family peptide receptor 2 Mus musculus 97-130 32774729-3 2020 In vitro and in vivo experiments were performed to examine the expression level and mechanism of relaxin family peptide receptor 2 (RXFP2) in the gubernaculum of fetal mice following diethylstilbestrol (DES) treatment. Diethylstilbestrol 183-201 relaxin/insulin-like family peptide receptor 2 Mus musculus 132-137 32774729-3 2020 In vitro and in vivo experiments were performed to examine the expression level and mechanism of relaxin family peptide receptor 2 (RXFP2) in the gubernaculum of fetal mice following diethylstilbestrol (DES) treatment. Diethylstilbestrol 203-206 relaxin/insulin-like family peptide receptor 2 Mus musculus 97-130 32774729-3 2020 In vitro and in vivo experiments were performed to examine the expression level and mechanism of relaxin family peptide receptor 2 (RXFP2) in the gubernaculum of fetal mice following diethylstilbestrol (DES) treatment. Diethylstilbestrol 203-206 relaxin/insulin-like family peptide receptor 2 Mus musculus 132-137 32774729-8 2020 In conclusion, DES affects the morphology and alters the gubernaculum structure, as well as the expression of RXFP2 protein. Diethylstilbestrol 15-18 relaxin/insulin-like family peptide receptor 2 Mus musculus 110-115 32774729-9 2020 These data demonstrate that DES is toxic to gubernaculum in fetal mice, and that RXFP2 is associated with the abnormal gubernaculum morphology induced by DES. Diethylstilbestrol 154-157 relaxin/insulin-like family peptide receptor 2 Mus musculus 81-86 22934511-0 2012 [Diethylstilbestrol affects LGR8 expression in mouse gubernaculum testis]. Diethylstilbestrol 1-19 relaxin/insulin-like family peptide receptor 2 Mus musculus 28-32 22934511-1 2012 OBJECTIVE: To investigate the impact of prenatal exposure to diethylstilbestrol (DES) on the specific receptor LGR8 of insulin-like factor 3 (INSL3) in the mouse gubernaculum testis, and that of exoestrogens on descensus testis in mice. Diethylstilbestrol 61-79 relaxin/insulin-like family peptide receptor 2 Mus musculus 111-115 22934511-1 2012 OBJECTIVE: To investigate the impact of prenatal exposure to diethylstilbestrol (DES) on the specific receptor LGR8 of insulin-like factor 3 (INSL3) in the mouse gubernaculum testis, and that of exoestrogens on descensus testis in mice. Diethylstilbestrol 81-84 relaxin/insulin-like family peptide receptor 2 Mus musculus 111-115 22934511-10 2012 CONCLUSION: Prenatal exposure to diethylstilbestrol affected the expression of LGR8 mRNA in the mouse gubernaculum testis, which suggests that diethylstilbestrol may induce cryptorchidism by interfering with the INSL3-LGR8 signaling system and consequently the development of the gubernaculum testis. Diethylstilbestrol 33-51 relaxin/insulin-like family peptide receptor 2 Mus musculus 79-83 22934511-10 2012 CONCLUSION: Prenatal exposure to diethylstilbestrol affected the expression of LGR8 mRNA in the mouse gubernaculum testis, which suggests that diethylstilbestrol may induce cryptorchidism by interfering with the INSL3-LGR8 signaling system and consequently the development of the gubernaculum testis. Diethylstilbestrol 143-161 relaxin/insulin-like family peptide receptor 2 Mus musculus 79-83 22934511-10 2012 CONCLUSION: Prenatal exposure to diethylstilbestrol affected the expression of LGR8 mRNA in the mouse gubernaculum testis, which suggests that diethylstilbestrol may induce cryptorchidism by interfering with the INSL3-LGR8 signaling system and consequently the development of the gubernaculum testis. Diethylstilbestrol 143-161 relaxin/insulin-like family peptide receptor 2 Mus musculus 218-222