PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19258390-6	2009	Interestingly, DAG to which PKD1 is recruited in this pathway is formed downstream of phospholipase D1 (PLD1) and a lipase-inactive PLD1 or inhibition of PLD1 by pharmacological inhibitors blocked PKD1 activation under oxidative stress.	Diglycerides	15-18	phospholipase D1	Homo sapiens	86-102	
22609963-0	2012	Diacylglycerol stimulates acrosomal exocytosis by feeding into a PKC- and PLD1-dependent positive loop that continuously supplies phosphatidylinositol 4,5-bisphosphate.	Diglycerides	0-14	phospholipase D1	Homo sapiens	74-78	
22609963-5	2012	Addition of diacylglycerol promotes the PKC-dependent activation of PLD1.	Diglycerides	12-26	phospholipase D1	Homo sapiens	68-72	
19258390-6	2009	Interestingly, DAG to which PKD1 is recruited in this pathway is formed downstream of phospholipase D1 (PLD1) and a lipase-inactive PLD1 or inhibition of PLD1 by pharmacological inhibitors blocked PKD1 activation under oxidative stress.	Diglycerides	15-18	phospholipase D1	Homo sapiens	104-108	
19258390-6	2009	Interestingly, DAG to which PKD1 is recruited in this pathway is formed downstream of phospholipase D1 (PLD1) and a lipase-inactive PLD1 or inhibition of PLD1 by pharmacological inhibitors blocked PKD1 activation under oxidative stress.	Diglycerides	15-18	phospholipase D1	Homo sapiens	132-136	
19258390-6	2009	Interestingly, DAG to which PKD1 is recruited in this pathway is formed downstream of phospholipase D1 (PLD1) and a lipase-inactive PLD1 or inhibition of PLD1 by pharmacological inhibitors blocked PKD1 activation under oxidative stress.	Diglycerides	15-18	phospholipase D1	Homo sapiens	132-136	
19258390-7	2009	To date it has been viewed that monosaturated and saturated DAG formed via PLD1 have no signaling function.	Diglycerides	60-63	phospholipase D1	Homo sapiens	75-79	
19258390-8	2009	However, our data describe a role for PLD1-induced DAG as a competent second messenger at the mitochondria that relays ROS to PKD1-mediated mitochondria-to-nucleus signaling.	Diglycerides	51-54	phospholipase D1	Homo sapiens	38-42	
11377832-4	2001	It has recently been shown that 1,25-dihydroxyvitamin D(3) specifically increases the expression/activity of phospholipase D-1, an enzyme that hydrolyzes phospholipids to generate lipid messengers, such as diacylglycerol (DAG).	Diglycerides	206-220	phospholipase D1	Homo sapiens	109-126	
11377832-4	2001	It has recently been shown that 1,25-dihydroxyvitamin D(3) specifically increases the expression/activity of phospholipase D-1, an enzyme that hydrolyzes phospholipids to generate lipid messengers, such as diacylglycerol (DAG).	Diglycerides	222-225	phospholipase D1	Homo sapiens	109-126	
35134390-1	2022	Classical phospholipase D (PLD) isoforms, PLD1 and PLD2, catalyze the hydrolysis of phosphatidylcholine (PC) to generate phosphatidic acid (PA) which can be further dephosphorylated to diacylglycerol (DAG).	Diglycerides	185-199	phospholipase D1	Homo sapiens	42-46	
35134390-1	2022	Classical phospholipase D (PLD) isoforms, PLD1 and PLD2, catalyze the hydrolysis of phosphatidylcholine (PC) to generate phosphatidic acid (PA) which can be further dephosphorylated to diacylglycerol (DAG).	Diglycerides	201-204	phospholipase D1	Homo sapiens	42-46