PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11292831-8 2001 Together, these data define a novel signaling pathway for M(1) mAChR, where increases in Ca(2+) and diacylglycerol stimulate the sequential activation of CalDAG-GEFI, Rap1, and B-Raf, resulting in the activation of MEK and ERK1/2. Diglycerides 100-114 B-Raf proto-oncogene, serine/threonine kinase Rattus norvegicus 177-182