PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10215634-1 1999 We investigated the cytochrome P-450-dependent metabolism of 1, 1-dichloroethylene (DCE) by human lung and liver microsomes and compared the results from analogous experiments in mice. ethylene dichloride 84-87 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 20-36 3787626-6 1986 Exposure to DSF alone decreased cytochrome P450 levels, but in combination with DCE, the decrement of cytochrome P450 was additive in a DCE concentration-dependent manner. ethylene dichloride 80-83 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 102-117 3787626-6 1986 Exposure to DSF alone decreased cytochrome P450 levels, but in combination with DCE, the decrement of cytochrome P450 was additive in a DCE concentration-dependent manner. ethylene dichloride 136-139 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 102-117 3787626-7 1986 However, depression of cytochrome P450 by DCE alone was not concentration dependent. ethylene dichloride 42-45 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 23-38