PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1703776-3	1990	In previous studies, expression of the human MDR1 gene has been shown to be regulated by heat shock, arsenite, and cadmium in a kidney carcinoma cell line, and mdr RNA is dramatically elevated in rat liver after partial hepatectomy or treatment of the animals with cytotoxic agents.	arsenite	101-109	ATP binding cassette subfamily B member 1	Homo sapiens	45-49	
1349537-0	1992	Quercetin, a bioflavonoid, inhibits the increase of human multidrug resistance gene (MDR1) expression caused by arsenite.	arsenite	112-120	ATP binding cassette subfamily B member 1	Homo sapiens	85-89	
1349537-4	1992	The increase of P-glycoprotein synthesis and MDR1 mRNA accumulation caused by exposure to arsenite were inhibited by quercetin.	arsenite	90-98	ATP binding cassette subfamily B member 1	Homo sapiens	16-30	
1349537-4	1992	The increase of P-glycoprotein synthesis and MDR1 mRNA accumulation caused by exposure to arsenite were inhibited by quercetin.	arsenite	90-98	ATP binding cassette subfamily B member 1	Homo sapiens	45-49	
1349537-5	1992	The CAT assay suggested that quercetin suppressed the transcriptional activation of the MDR1 gene after exposure to arsenite.	arsenite	116-124	ATP binding cassette subfamily B member 1	Homo sapiens	88-92	
1360409-3	1992	Deletion analysis of the MDR1 promoter indicated that the transcriptional activation after exposure to arsenite depends on a 60-bp region containing two heat-shock responsive elements.	arsenite	103-111	ATP binding cassette subfamily B member 1	Homo sapiens	25-29	
11205256-7	2000	A variety of stimuli increase the expression of the mdr1 gene: lowered extracellular pH, heat shock, arsenite, cytotoxic agents, anticancer drugs, transfection with oncogenes, HIV-I, and UV-irradiation.	arsenite	101-109	ATP binding cassette subfamily B member 1	Homo sapiens	52-56	
1967174-0	1990	Heat shock and arsenite increase expression of the multidrug resistance (MDR1) gene in human renal carcinoma cells.	arsenite	15-23	ATP binding cassette subfamily B member 1	Homo sapiens	73-77	
16121039-0	2005	Arsenite regulates Cystic Fibrosis Transmembrane Conductance Regulator and P-glycoprotein: evidence of pathway independence.	arsenite	0-8	ATP binding cassette subfamily B member 1	Homo sapiens	75-89	
16121039-5	2005	The goal of this study was to investigate the effects of trivalent arsenic (arsenite), a known transcriptional activator of Pgp, on CFTR expression.	arsenite	76-84	ATP binding cassette subfamily B member 1	Homo sapiens	124-127	
16121039-11	2005	Thus, the regulatory pathways that control functional expression of CFTR and P-glycoprotein following arsenite treatment in T-84 cells are distinct and independent.	arsenite	102-110	ATP binding cassette subfamily B member 1	Homo sapiens	77-91	
7891750-2	1994	The first P-glycoprotein related gene described in Leishmania was ltpgpA, a gene frequently amplified in arsenite resistant Leishmania.	arsenite	105-113	ATP binding cassette subfamily B member 1	Homo sapiens	10-24