PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30090515-7	2017	In addition, ATF2 knockdown did not decrease the expressions of pro-inflammatory cytokines induced by arsenite in SV-HUC-1 cells, but dramatically increased mRNA expressions of TNFalpha, TGFalpha and IL-8 under arsenite and non-arsenite conditions.	arsenite	211-219	C-X-C motif chemokine ligand 8	Homo sapiens	200-204	
27913196-10	2017	In addition, miR-155, IL-6, and IL-8 were over-expressed in the serum of arsenite exposure group.	arsenite	73-81	C-X-C motif chemokine ligand 8	Homo sapiens	32-36	
30090515-7	2017	In addition, ATF2 knockdown did not decrease the expressions of pro-inflammatory cytokines induced by arsenite in SV-HUC-1 cells, but dramatically increased mRNA expressions of TNFalpha, TGFalpha and IL-8 under arsenite and non-arsenite conditions.	arsenite	211-219	C-X-C motif chemokine ligand 8	Homo sapiens	200-204	
22354777-0	2013	Phosphorylation of histone H3 at serine 10 has an essential role in arsenite-induced expression of FOS, EGR1 and IL8 mRNA in cultured human cell lines.	arsenite	68-76	C-X-C motif chemokine ligand 8	Homo sapiens	113-116	
23811328-4	2013	The results showed that, on acute or chronic exposure to arsenite, HBE cells over-expressed the pro-inflammatory cytokines, interleukin-6 (IL-6), interleukin-8 (IL-8), and interleukin-1beta (IL-1beta).	arsenite	57-65	C-X-C motif chemokine ligand 8	Homo sapiens	146-159	
23811328-4	2013	The results showed that, on acute or chronic exposure to arsenite, HBE cells over-expressed the pro-inflammatory cytokines, interleukin-6 (IL-6), interleukin-8 (IL-8), and interleukin-1beta (IL-1beta).	arsenite	57-65	C-X-C motif chemokine ligand 8	Homo sapiens	161-165	
23811328-6	2013	Moreover, IL-6 and IL-8 were essential for the malignant progression of arsenite-transformed HBE cells.	arsenite	72-80	C-X-C motif chemokine ligand 8	Homo sapiens	19-23	
24284797-9	2014	Interestingly, treatment of HCT116 cells with a small interference RNA specifically targeting SRSF3-PTC mRNA significantly attenuated arsenite-stimulated induction of c-JUN protein, its binding activity to the AP-1 binding site (-126 to 120 bp) in the interleukin (IL)-8 gene promoter, and AP-1 promoter activity, resulting in significant reduction of arsenite-stimulated IL-8 production.	arsenite	134-142	C-X-C motif chemokine ligand 8	Homo sapiens	252-270	
24284797-9	2014	Interestingly, treatment of HCT116 cells with a small interference RNA specifically targeting SRSF3-PTC mRNA significantly attenuated arsenite-stimulated induction of c-JUN protein, its binding activity to the AP-1 binding site (-126 to 120 bp) in the interleukin (IL)-8 gene promoter, and AP-1 promoter activity, resulting in significant reduction of arsenite-stimulated IL-8 production.	arsenite	134-142	C-X-C motif chemokine ligand 8	Homo sapiens	372-376	
10775461-6	2000	Exposing the cells to 500 microM arsenite, prior to adding TNF-alpha, completely inhibited IkappaBalpha degradation, NF-kappaB translocation, NF-kappaB-dependent gene transcription, and transcription of the endogenous gene for IL-8.	arsenite	33-41	C-X-C motif chemokine ligand 8	Homo sapiens	227-231	
30442959-10	2018	tRF5-AlaCGC activates p65, subsequently leading to enhanced secretion of IL-8 in arsenite response.	arsenite	81-89	C-X-C motif chemokine ligand 8	Homo sapiens	73-77	
10521501-0	1999	Arsenite exposure of cultured airway epithelial cells activates kappaB-dependent interleukin-8 gene expression in the absence of nuclear factor-kappaB nuclear translocation.	arsenite	0-8	C-X-C motif chemokine ligand 8	Homo sapiens	81-94