PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10585430-7 1999 Mutation of GHR"s membrane-proximal tyrosine residues 333 and 338 to phenylalanine suppressed the inhibition by SOCS-3, but not by CIS, of GH signaling to STAT5b. Phenylalanine 69-82 growth hormone 1 Homo sapiens 12-14 11502827-5 2001 We also discovered a novel G6191 to T missense mutation in exon 4 of GH-1 that changes valine 110, which is highly conserved in mammalian and several nonmammalian GH, to phenylalanine. Phenylalanine 170-183 growth hormone 1 Homo sapiens 69-73 11147801-8 2001 There was a net release of phenylalanine across the forearm, and the negative phenylalanine balance was higher during fasting with GH suppression (balance: basal 9 +/- 3, fast 15 +/- 6, fast-GH 17 +/- 4, and fast+GH 11 +/- 5 nmol/min, P < 0.05). Phenylalanine 78-91 growth hormone 1 Homo sapiens 131-133 11147801-11 2001 In summary, we find that suppression of GH during fasting leads to a 50% increase in urea-nitrogen excretion, together with an increased net release and appearance rate of phenylalanine across the forearm. Phenylalanine 172-185 growth hormone 1 Homo sapiens 40-42 10722114-0 2000 A new, electrophoretically silent, fetal hemoglobin variant: Hb F-Calabria [Ggamma118(GH1)Phe-->Leu]. Phenylalanine 90-93 growth hormone 1 Homo sapiens 86-89 10722114-1 2000 Hb F-Calabria [Ggamma118(GH1)Phe-->Leu] is a new fetal hemoglobin variant that was found during routine screening for abnormal hemoglobins in a newborn of Calabrian (Southern Italy) ancestry. Phenylalanine 29-32 growth hormone 1 Homo sapiens 25-28 10722114-3 2000 Sequencing of the polymerase chain reaction-amplified exon 3 of the Ggamma-globin gene demonstrated the TTC-->CTC mutation at codon 118 leading to the Phe-->Leu conservative substitution at position GH1. Phenylalanine 154-157 growth hormone 1 Homo sapiens 205-208 8190022-1 1994 The in vitro effect of a hypoglycaemic fragment of human growth hormone containing the sequence H2N-Leu-Ser-Arg-Leu-Phe-Asu11-Asn-Ala-COOH (Asu11-hGH 6-13) on tyrosine kinase of rat hepatic insulin receptors was examined. Phenylalanine 116-119 growth hormone 1 Homo sapiens 57-71 10490141-0 1999 Hb Harrow [beta118(GH1)Phe-->Cys]: a new neutral hemoglobin variant. Phenylalanine 23-26 growth hormone 1 Homo sapiens 19-22 24193988-1 1996 This paper reports on the effect of administration of mammalian growth hormone (GH) on muscle protein synthesis as measured in white muscle using the phenylalanine flooding technique. Phenylalanine 150-163 growth hormone 1 Homo sapiens 64-78 24193988-1 1996 This paper reports on the effect of administration of mammalian growth hormone (GH) on muscle protein synthesis as measured in white muscle using the phenylalanine flooding technique. Phenylalanine 150-163 growth hormone 1 Homo sapiens 80-82 7829265-1 1995 Phenylacetate, a natural metabolite of phenylalanine which was originally described as a plant growth hormone, has recently gained attention as a possible differentiation inducer for a variety of human tumor cell types. Phenylalanine 39-52 growth hormone 1 Homo sapiens 95-109 1607069-2 1992 GH was infused into the brachial artery for 6 h with a dose that, in a previous study, stimulated muscle protein synthesis (phenylalanine Rd) without affecting systemic GH, insulin, or insulinlike growth factor I concentrations. Phenylalanine 124-137 growth hormone 1 Homo sapiens 0-2 8358331-1 1993 The synthetic C-terminal peptide fragment of human growth hormone, Leu-Arg-Ile-Val Gln-Cys-Arg-Val-Ser-Glu-Gly-Ser-Cys-Gly-Phe (hGH 177-191), was shown to have antilipogenic activity identical with that of the intact molecule of human growth hormone (hGH). Phenylalanine 123-126 growth hormone 1 Homo sapiens 51-65 1607069-5 1992 Glucose uptake by forearm tissues in response to GH and insulin did not change significantly between 3 and 6 h. By 6 h, the combined infusion of GH and insulin promoted a significantly more positive net balance of phenylalanine, leucine, isoleucine, and valine (all P less than 0.05). Phenylalanine 214-227 growth hormone 1 Homo sapiens 145-147 3342241-6 1988 The partial amino-acid sequence from the protein completely agrees with that derived from the cDNA, with Phe as the first residue in mature duck GH preceded by a 27-residue hydrophobic signal peptide. Phenylalanine 105-108 growth hormone 1 Homo sapiens 145-147 1719554-7 1991 Our findings suggest that these mutant GHRs fail to follow the correct intracellular transport pathway and underline the potential importance of this phenylalanine residue, which is conserved among the GH, prolactin, and erythropoietin receptors that belong to the same cytokine receptor superfamily. Phenylalanine 150-163 growth hormone 1 Homo sapiens 39-41 2003602-5 1991 After 6 h, GH suppressed forearm net release (3 vs. 6 h) of Phe (P less than 0.05), Leu (P less than 0.01), total branched-chain amino acids (P less than 0.025), and essential neutral amino acids (0.05 less than P less than 0.1). Phenylalanine 60-63 growth hormone 1 Homo sapiens 11-13 3667327-0 1987 A second family with Hb Minneapolis-Laos or alpha 2 beta (2)118(GH1)Phe----Tyr. Phenylalanine 68-71 growth hormone 1 Homo sapiens 64-67 4091848-1 1985 Evidence is presented that the hypoglycemic action of the human growth hormone fragment, Ile-Pro-Leu-Ser-Arg-Leu-Phe-Asp-Asn-Ala (hGH 4-15) is due to the interaction of hGH 4-15 with plasma membrane resulting in a time- and temperature-dependent release of a cellular mediator which acts to increase insulin binding and hexose transport with consequent potentiation of insulin action. Phenylalanine 113-116 growth hormone 1 Homo sapiens 64-78 3569692-1 1986 The in vivo and in vitro effects of a hypoglycaemic fragment of human growth hormone containing the sequence H2N-Ile-Pro-Leu-Ser-Arg-Leu-Phe-Asp-Asn-Ala-Met-Leu-COOH (hGH 4-15) on 2-deoxy-[1-14C]-D-glucose uptake in adipocytes were studied. Phenylalanine 137-140 growth hormone 1 Homo sapiens 70-84 6341118-1 1983 A synthetic amino-terminal fragment of human growth hormone (hGH) containing the sequence H2N-Leu-Ser-Arg-Leu-Phe-Asp-Asn-Ala-COOH (hGH 6-13) was shown to increase [125I]iodoinsulin binding to rat hepatic receptors in vivo. Phenylalanine 110-113 growth hormone 1 Homo sapiens 45-59 5347431-0 1969 Changes in plasma growth hormone after a phenylalanine tolerance test in normal and phenylketonuric children. Phenylalanine 41-54 growth hormone 1 Homo sapiens 18-32 7183441-0 1982 [Effect of growth hormone on the transport of leucine and phenylalanine through the erythrocyte membrane in children with hypothalamo-hypophyseal insufficiency]. Phenylalanine 58-71 growth hormone 1 Homo sapiens 11-25 6776995-4 1980 The natural or synthetic Gly-Lys-Val-Asn and Phe-Glu-His-Glu had some growth hormone releasing activity while Val-Trp, Tyr-Phe and Lys-Phe-Tyr had slight prolactin releasing activity. Phenylalanine 45-49 growth hormone 1 Homo sapiens 70-84 16742415-15 1966 End-group analysis of purified growth hormone and its components showed only phenylalanine at both N- and C-terminals. Phenylalanine 77-90 growth hormone 1 Homo sapiens 31-45 27311878-1 2016 The recognition of human growth hormone (hGH) by the synthetic host molecule cucurbit[7]uril (Q7) was predicted on the basis of its N-terminal phenylalanine. Phenylalanine 143-156 growth hormone 1 Homo sapiens 25-39 33878389-2 2021 We used human growth hormone (hGH) as target protein that contains two internal disulfide bridges and an N-terminal phenylalanine. Phenylalanine 116-129 growth hormone 1 Homo sapiens 14-28