PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16854049-0	2006	Aromatic interactions with phenylalanine 691 and cysteine 828: a concept for FMS-like tyrosine kinase-3 inhibition.	Phenylalanine	27-40	fms related receptor tyrosine kinase 3	Homo sapiens	77-103	
18628457-6	2008	RESULT: The substitution of the tyrosine residues by phenylalanine in the juxtamembrane, interkinase, and COOH-terminal domains resulted in a complete loss of the transforming potential of FLT3-D835Y-expressing cells which can be attributed to a significant reduction of signal tranducer and activator of transcription 5 (STAT5) phosphorylation at the molecular level.	Phenylalanine	53-66	fms related receptor tyrosine kinase 3	Homo sapiens	189-193	
18628457-8	2008	Combined mutation of Y589 and Y591 to phenylalanine also abrogated ligand-dependent proliferation of FLT3-WT and the transforming potential of FLT3-ITD-with a subsequent abrogation of STAT5 phosphorylation.	Phenylalanine	38-51	fms related receptor tyrosine kinase 3	Homo sapiens	101-105	
18628457-8	2008	Combined mutation of Y589 and Y591 to phenylalanine also abrogated ligand-dependent proliferation of FLT3-WT and the transforming potential of FLT3-ITD-with a subsequent abrogation of STAT5 phosphorylation.	Phenylalanine	38-51	fms related receptor tyrosine kinase 3	Homo sapiens	143-147	
15180525-8	2004	STI571 binding to Flt3 is prevented by the phenylalanine 691 side-chain in the ATP binding center and mutating this site to threonine renders the corresponding Flt3 mutant sensitive to STI571.	Phenylalanine	43-56	fms related receptor tyrosine kinase 3	Homo sapiens	18-22	
15374944-6	2004	FLT3 proteins mutated at Ala-627, Asn-676, or Phe-691 remained sensitive to higher concentrations of the inhibitors, but the G697R mutation conferred high-level resistance to each of these inhibitors as well as to six additional experimental inhibitors.	Phenylalanine	46-49	fms related receptor tyrosine kinase 3	Homo sapiens	0-4	
35387260-6	2022	Results: The A-loop of the FLT3 protein may experience conformational change in the presence of the resistant mutation, which were mainly positioned at PHE-830.	Phenylalanine	152-155	fms related receptor tyrosine kinase 3	Homo sapiens	27-31	
12435730-4	2003	It was predicted that Flt3 Phe-691 in the beta5 strand may sterically prevent interaction with STI-571.	Phenylalanine	27-30	fms related receptor tyrosine kinase 3	Homo sapiens	22-26