PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12694532-7 2003 We found that both adenine and 2"-dA, but none of the other 2"-deoxynucleosides, inhibited the kinase activity of ATR, similar to that of caffeine. 2'-deoxyadenosine 31-36 serine/threonine-protein kinase ATR Mesocricetus auratus 114-117 12694532-0 2003 Caffeine mimics adenine and 2"-deoxyadenosine, both of which inhibit the guanine-nucleotide exchange activity of RCC1 and the kinase activity of ATR. 2'-deoxyadenosine 28-45 serine/threonine-protein kinase ATR Mesocricetus auratus 145-148 12694532-9 2003 CONCLUSION: The effect of caffeine on cell-cycle control mimics the biological effect of adenine and 2"-dA, both of which inhibit ATR. 2'-deoxyadenosine 101-106 serine/threonine-protein kinase ATR Mesocricetus auratus 130-133 12694532-10 2003 dATP, a final metabolite of adenine and 2"-dA, is suggested to inhibit ATR, resulting in PCC. 2'-deoxyadenosine 40-45 serine/threonine-protein kinase ATR Mesocricetus auratus 71-74