PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1448929-5	1992	These results suggest that nsP2 is a papain-like proteinase whose catalytic dyad is composed of Cys-481 and His-558.	Cysteine	96-99	reticulon 2	Homo sapiens	27-31	
31561412-1	2019	The papain-like cysteine protease 2 (PLP2) within the N-terminus of the porcine reproductive and respiratory syndrome virus (PRRSV) nsp2 replicase protein specifies a deubiquitinating enzyme (DUB), but its biochemical properties and the role in infection have remained poorly defined.	Cysteine	16-24	reticulon 2	Homo sapiens	132-136	
27845418-0	2016	Chikungunya virus infectivity, RNA replication and non-structural polyprotein processing depend on the nsP2 protease"s active site cysteine residue.	Cysteine	131-139	reticulon 2	Homo sapiens	103-107	
26597768-4	2015	Classically the alphavirus nsP2 protease is thought to be papain-like with the enzyme reaction proceeding through a cysteine/histidine catalytic dyad.	Cysteine	116-124	reticulon 2	Homo sapiens	27-31	
21543324-7	2011	Nevertheless, the catalytic cysteine and histidine residues constitute an active site that is highly similar to these in papain-like and nsP2 proteases.	Cysteine	28-36	reticulon 2	Homo sapiens	137-141	
19587037-6	2009	Introduction of targeted amino acid mutations in the protease domain confirmed the importance of the putative Cys(55)- His(124) catalytic motif for nsp2/3 proteolysis in vitro, as were three additional conserved cysteine residues (Cys(111), Cys(142), and Cys(147)).	Cysteine	110-113	reticulon 2	Homo sapiens	148-152