PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9356471-4 1997 The Piedmontese myostatin sequence contains a missense mutation in exon 3, resulting in a substitution of tyrosine for an invariant cysteine in the mature region of the protein. Cysteine 132-140 myostatin Bos taurus 16-25 26305245-2 2015 Piedmontese cattle breeds have a missense mutation, which results in a cysteine to tyrosine substitution in the mature myostatin protein (C313Y). Cysteine 71-79 myostatin Bos taurus 119-128 19160084-4 2009 Piedmontese cattle shows a nucleotide transition G --> A (G938A) at exon 3, resulting in the substitution of cysteine to tyrosine, leading to a protein structure change, which determines myostatin inactivation and consequent muscular hypertrophy. Cysteine 112-120 myostatin Bos taurus 190-199 12055081-0 2002 Single cysteine to tyrosine transition inactivates the growth inhibitory function of Piedmontese myostatin. Cysteine 7-15 myostatin Bos taurus 97-106 12055081-2 2002 Piedmontese cattle are a heavy-muscled breed that express a mutated form of myostatin in which cysteine (313) is substituted with tyrosine. Cysteine 95-103 myostatin Bos taurus 76-85 12055081-10 2002 These results indicate that, in Piedmontese myostatin, substitution of cysteine with tyrosine results in the distortion of the "cystine knot" structure and a loss of biological activity of the myostatin. Cysteine 71-79 myostatin Bos taurus 44-53 12055081-10 2002 These results indicate that, in Piedmontese myostatin, substitution of cysteine with tyrosine results in the distortion of the "cystine knot" structure and a loss of biological activity of the myostatin. Cysteine 71-79 myostatin Bos taurus 193-202