PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19706767-6	2009	Addition of DTT or glutathione prevents the JAK cross-linking and blocks the inhibitory effects of HJB on IL-6-induced STAT3 activation, suggesting that HJB may react with cystein residues of JAKs to form covalent bonds that inactivate JAKs.	Cysteine	172-179	Janus kinase 1	Homo sapiens	192-196	
22905257-1	2012	We previously showed that oxidative stress inhibits leukemia inhibitory factor (LIF) signaling by targeting JAK1, and the catalytic domains of JAK 1 and 2 have a cysteine-based redox switch.	Cysteine	162-170	Janus kinase 1	Homo sapiens	143-154	
18413761-4	2008	In support of a direct mechanism, CDDO-Me forms adducts with JAK1 at Cys(1077) in the kinase domain and inhibits JAK1 activity.	Cysteine	69-72	Janus kinase 1	Homo sapiens	61-65	
35235776-7	2022	Importantly, JAK1 was directly modified by itaconate derivatives at multiple residues, including cysteines 715, 816, 943, and 1130.	Cysteine	97-106	Janus kinase 1	Homo sapiens	13-17