PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22728921-10	2012	These results suggest that the phenol NPrCAP, acting as a prohapten, can be activated in melanoma cells by tyrosinase to the quinone-hapten NPrCAQ, which binds to melanosomal proteins through their cysteine residues to form possible neo-antigens, thus triggering the immunological response.	Cysteine	198-206	tyrosinase	Mus musculus	107-117	
2511568-5	1989	It was shown that sulphydryl compounds such as cysteine and glutathione have an inhibitory effect on tyrosinase, and it is possible that the elevated levels of SH-compounds are responsible for a reduction in tyrosinase activity in agouti mice.	Cysteine	47-55	tyrosinase	Mus musculus	101-111	
2511568-5	1989	It was shown that sulphydryl compounds such as cysteine and glutathione have an inhibitory effect on tyrosinase, and it is possible that the elevated levels of SH-compounds are responsible for a reduction in tyrosinase activity in agouti mice.	Cysteine	47-55	tyrosinase	Mus musculus	208-218	
2431571-1	1986	The dopa oxidase activity of tyrosinase in the skin from albino and black mice was assayed using a technique based on the formation of two diastereomers of 5-S-cysteinyldopa when incubating tissue extracts with both L-dopa and D-dopa as substrates in the presence of cysteine.	Cysteine	267-275	tyrosinase	Mus musculus	29-39	
4965126-0	1967	In vitro growth inhibition of S-91 mouse melanomas by tyrosinase substrate analogs with and without L-cysteine.	Cysteine	100-110	tyrosinase	Mus musculus	54-64	
15007389-5	2004	Transgenic expression of the functional Tyr(Cys) allele in albino mice (Tyr(Ser)) caused a reduction in skin papilloma multiplicity, in four independent experiments and at three dose levels of DMBA (9,10-dimethyl-1,2-benzanthracene).	Cysteine	44-47	tyrosinase	Mus musculus	40-43	
15007389-5	2004	Transgenic expression of the functional Tyr(Cys) allele in albino mice (Tyr(Ser)) caused a reduction in skin papilloma multiplicity, in four independent experiments and at three dose levels of DMBA (9,10-dimethyl-1,2-benzanthracene).	Cysteine	44-47	tyrosinase	Mus musculus	72-75	
9853616-3	1998	Melanocytes derived from albino mice contain a homozygous point mutation (TGT-->TCT) in the tyrosinase gene, resulting in an amino acid change from Cys-->Ser.	Cysteine	151-154	tyrosinase	Mus musculus	95-105	
2124349-0	1990	Conserved cysteine to serine mutation in tyrosinase is responsible for the classical albino mutation in laboratory mice.	Cysteine	10-18	tyrosinase	Mus musculus	41-51	
2110899-3	1990	Sequence analysis of this gene reveals a point mutation at nucleotide residue 387 (G----C transversion) causing a Cys----Ser substitution at position 85 in one of the cysteine-rich domains of the tyrosinase molecule.	Cysteine	114-117	tyrosinase	Mus musculus	196-206	
2110899-3	1990	Sequence analysis of this gene reveals a point mutation at nucleotide residue 387 (G----C transversion) causing a Cys----Ser substitution at position 85 in one of the cysteine-rich domains of the tyrosinase molecule.	Cysteine	167-175	tyrosinase	Mus musculus	196-206	
2245916-7	1990	This mutation is adjacent to another cysteine at which, in the analogous position in tyrosinase a mutation results in the albino phenotype.	Cysteine	37-45	tyrosinase	Mus musculus	85-95