PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20644162-7 2010 CD33(+) cells with potent suppressive capacity were best generated in vitro by GM-CSF and IL-6, and secondarily by GM-CSF + IL-1beta, PGE(2), TNF-alpha, or VEGF. Prostaglandins E 134-137 CD33 molecule Homo sapiens 0-4 21972293-2 2011 In the present study, we report that the establishment of a positive feedback loop between prostaglandin E(2) (PGE(2)) and cyclooxygenase 2 (COX2), the key regulator of PGE(2) synthesis, represents the determining factor in redirecting the development of CD1a(+) DCs to CD14(+)CD33(+)CD34(+) monocytic MDSCs. Prostaglandins E 111-114 CD33 molecule Homo sapiens 277-281 21972293-2 2011 In the present study, we report that the establishment of a positive feedback loop between prostaglandin E(2) (PGE(2)) and cyclooxygenase 2 (COX2), the key regulator of PGE(2) synthesis, represents the determining factor in redirecting the development of CD1a(+) DCs to CD14(+)CD33(+)CD34(+) monocytic MDSCs. Prostaglandins E 169-172 CD33 molecule Homo sapiens 277-281