PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25178484-5 2014 Expression of CBL(K382E), CBL(D390Y), or CBL(R420Q) in COS-7 cells resulted in increased levels of surface EGFR and reduced amounts of intracellular EGFR; both consequences indicate ineffective EGFR internalization. carbonyl sulfide 55-58 Cbl proto-oncogene Homo sapiens 14-17 10617633-7 2000 Point mutations of conserved cysteine residues or a histidine in the RING finger domain, which are required for zinc binding, abrogated the ability of Cbl to negatively regulate Syk in COS-7 cells and Ramos B lymphocytic cells. carbonyl sulfide 185-188 Cbl proto-oncogene Homo sapiens 151-154