PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26233912-5	2015	In the immune system, the ALDH1A and CYP26 enzymes appear to modulate RA concentrations.	Radium	70-72	cytochrome P450 family 26 subfamily A member 1	Homo sapiens	37-42	
27775549-3	2016	We previously showed that expression of CYP26 in BM stromal cells maintains a retinoic acid-low (RA-low) microenvironment that prevents the differentiation of normal and malignant hematopoietic cells.	Radium	97-99	cytochrome P450 family 26 subfamily A member 1	Homo sapiens	40-45	
27775549-5	2016	CYP26-mediated inactivation of RA within the BM microenvironment prevented plasma cell differentiation and promoted a B cell-like, BTZ-resistant phenotype in human MM cells that were cocultured on BM stroma.	Radium	31-33	cytochrome P450 family 26 subfamily A member 1	Homo sapiens	0-5	
18606996-8	2008	These extracts contained retinoids (5.4 nM) as assessed by RA-inducible Cyp26A1-promoter luciferase reporter cell lines.	Radium	59-61	cytochrome P450 family 26 subfamily A member 1	Homo sapiens	72-79	
25217584-2	2014	We have studied the effect of activation of the retinoic A receptor, at the RARE-promoter chromatin of CASP9 and CYP26A1 genes, 15 and 45 min following RA exposure, and we found that histone H3 lysines 4 and 9 are demethylated by the lysine-specific demethylase, LSD1 and by the JMJ-domain containing demethylase, D2A.	Radium	76-78	cytochrome P450 family 26 subfamily A member 1	Homo sapiens	113-120	
18816852-3	2008	These have shown local control of synthesis and degradation, and computational models suggest that degradation by the Cyp26 enzymes plays a critical role in the formation of a morphogen gradient as well as its ability to compensate for fluctuations in RA levels.	Radium	252-254	cytochrome P450 family 26 subfamily A member 1	Homo sapiens	118-123	
14532297-11	2004	This third CYP26 member may play a specific role in catabolizing both all-trans and 9-cis isomers of RA.	Radium	101-103	cytochrome P450 family 26 subfamily A member 1	Homo sapiens	11-16	
14692511-2	2003	Several of the compounds were weak inhibitors of the non-specific rat liver microsomal P450 enzymes and moderate inhibitors of the RA-induced enzymes in cultured human genital fibroblasts, where the RA-specific enzyme CYP26 is probably expressed.	Radium	131-133	cytochrome P450 family 26 subfamily A member 1	Homo sapiens	218-223	
14692511-2	2003	Several of the compounds were weak inhibitors of the non-specific rat liver microsomal P450 enzymes and moderate inhibitors of the RA-induced enzymes in cultured human genital fibroblasts, where the RA-specific enzyme CYP26 is probably expressed.	Radium	199-201	cytochrome P450 family 26 subfamily A member 1	Homo sapiens	218-223