PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24768768-2	2014	Our previous studies showed that HPS stimulates proliferation of hepatocytes in an ERK pathway-dependent manner.	hps	33-36	EPH receptor B2	Homo sapiens	83-86	
24768768-3	2014	However, the molecular mechanism of HPS-induced activation of the ERK pathway remains unclear.	hps	36-39	EPH receptor B2	Homo sapiens	66-69	
24768768-5	2014	Specific inhibition of EGFR kinase activity by gefitinib or down-regulation of EGFR by specific EGFR siRNAs prevented HPS-induced activation of the ERK pathway and proliferation of L02 cells.	hps	118-121	EPH receptor B2	Homo sapiens	148-151	
24768768-6	2014	Furthermore, inhibition of Src activity significantly blocked HPS-induced activation of the EGFR, which was suggestive of a ligand-independent transactivation mechanism of EGFR itself as well as ERK phosphorylation and proliferation of L02 cells.	hps	62-65	EPH receptor B2	Homo sapiens	195-198