PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8695221-6 1996 In contrast, the level of ERBB2 mRNA and protein in cell lysates was not stimulated, but was transiently suppressed by toremifene. Toremifene 119-129 erb-b2 receptor tyrosine kinase 2 Homo sapiens 26-31 8695221-9 1996 These results show that shedding of ECD is an additional level of regulation of ERBB2 by the anti-oestrogen toremifene. Toremifene 108-118 erb-b2 receptor tyrosine kinase 2 Homo sapiens 80-85 1680817-6 1991 The anti-estrogens toremifene and tamoxifen inhibited estrogen induction of pS2 expression, down-regulation of erbB2 expression and proliferation of the ZR-75-I cells in a concentration-dependent manner. Toremifene 19-29 erb-b2 receptor tyrosine kinase 2 Homo sapiens 111-116 1680817-10 1991 Concomitant administration of toremifene or tamoxifen increased erbB2 mRNA and abolished pS2 mRNA. Toremifene 30-40 erb-b2 receptor tyrosine kinase 2 Homo sapiens 64-69 22740857-18 2012 A longer duration of adjuvant AI therapy and negative HER2 overexpression may, with further studies, be beneficial as positive predictive factors for the effectiveness of TOR treatment. Toremifene 171-174 erb-b2 receptor tyrosine kinase 2 Homo sapiens 54-58