PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
14712290-7	2004	The mechanism of action appears to involve imatinib inhibition of c-abl kinase activity with an associated decrease in CLB-induced Rad51 phosphorylation and CLB-induced Rad51 nuclear foci, suggesting that imatinib decreases Rad51-related DNA repair of CLB-induced DNA lesions.	Chlorambucil	119-122	RAD51 recombinase	Homo sapiens	131-136	
14712290-7	2004	The mechanism of action appears to involve imatinib inhibition of c-abl kinase activity with an associated decrease in CLB-induced Rad51 phosphorylation and CLB-induced Rad51 nuclear foci, suggesting that imatinib decreases Rad51-related DNA repair of CLB-induced DNA lesions.	Chlorambucil	157-160	RAD51 recombinase	Homo sapiens	169-174	
14712290-7	2004	The mechanism of action appears to involve imatinib inhibition of c-abl kinase activity with an associated decrease in CLB-induced Rad51 phosphorylation and CLB-induced Rad51 nuclear foci, suggesting that imatinib decreases Rad51-related DNA repair of CLB-induced DNA lesions.	Chlorambucil	157-160	RAD51 recombinase	Homo sapiens	169-174	
14712290-7	2004	The mechanism of action appears to involve imatinib inhibition of c-abl kinase activity with an associated decrease in CLB-induced Rad51 phosphorylation and CLB-induced Rad51 nuclear foci, suggesting that imatinib decreases Rad51-related DNA repair of CLB-induced DNA lesions.	Chlorambucil	157-160	RAD51 recombinase	Homo sapiens	169-174	
14712290-7	2004	The mechanism of action appears to involve imatinib inhibition of c-abl kinase activity with an associated decrease in CLB-induced Rad51 phosphorylation and CLB-induced Rad51 nuclear foci, suggesting that imatinib decreases Rad51-related DNA repair of CLB-induced DNA lesions.	Chlorambucil	157-160	RAD51 recombinase	Homo sapiens	169-174	
12007561-2	2002	We have demonstrated previously that increased chlorambucil (CLB)-induced HsRad51 nuclear foci formation correlated with a CLB-resistant phenotype in B-CLL lymphocytes.	Chlorambucil	47-59	RAD51 recombinase	Homo sapiens	74-81	
12007561-2	2002	We have demonstrated previously that increased chlorambucil (CLB)-induced HsRad51 nuclear foci formation correlated with a CLB-resistant phenotype in B-CLL lymphocytes.	Chlorambucil	61-64	RAD51 recombinase	Homo sapiens	74-81	
12007561-2	2002	We have demonstrated previously that increased chlorambucil (CLB)-induced HsRad51 nuclear foci formation correlated with a CLB-resistant phenotype in B-CLL lymphocytes.	Chlorambucil	123-126	RAD51 recombinase	Homo sapiens	74-81	
12007561-3	2002	In this report, we measured the protein levels of HsRad51 and Xrcc3 (an HsRad51 paralog) and correlated them with the in vitro CLB cytotoxicity (LD(50)) in lymphocytes from seventeen B-CLL patients.	Chlorambucil	127-130	RAD51 recombinase	Homo sapiens	50-57	
12007561-3	2002	In this report, we measured the protein levels of HsRad51 and Xrcc3 (an HsRad51 paralog) and correlated them with the in vitro CLB cytotoxicity (LD(50)) in lymphocytes from seventeen B-CLL patients.	Chlorambucil	127-130	RAD51 recombinase	Homo sapiens	72-79	
12007561-4	2002	Both HsRad51 (r=0.75, P=0.0005) and Xrcc3 (r=0.52, P=0.03) protein levels correlated with the in vitro CLB LD(50).	Chlorambucil	103-106	RAD51 recombinase	Homo sapiens	5-12	
8679556-2	1996	Oligodeoxyribonucleotides (ODNs) bearing the reactive nitrogen mustard chlorambucil have been used as sequence-directed affinity labeling reagents to investigate the length and homology requirements for RecA-catalyzed alkylation of double-stranded DNA.	Chlorambucil	71-83	RAD51 recombinase	Homo sapiens	203-207	
10473103-0	1999	Chlorambucil induction of HsRad51 in B-cell chronic lymphocytic leukemia.	Chlorambucil	0-12	RAD51 recombinase	Homo sapiens	26-33	
10473103-5	1999	We have analyzed the intracellular distribution of HsRad51 protein in these lymphocytes before and after treatment with CLB by immunofluorescence.	Chlorambucil	120-123	RAD51 recombinase	Homo sapiens	51-58	
10473103-7	1999	In the CLB-resistant CLL lymphocytes, there was a linear correlation between induction of Rad51 protein at 5.4 microM CLB and the in vitro LD50 dose of CLB.	Chlorambucil	7-10	RAD51 recombinase	Homo sapiens	90-95	
10473103-7	1999	In the CLB-resistant CLL lymphocytes, there was a linear correlation between induction of Rad51 protein at 5.4 microM CLB and the in vitro LD50 dose of CLB.	Chlorambucil	118-121	RAD51 recombinase	Homo sapiens	90-95	
10473103-7	1999	In the CLB-resistant CLL lymphocytes, there was a linear correlation between induction of Rad51 protein at 5.4 microM CLB and the in vitro LD50 dose of CLB.	Chlorambucil	118-121	RAD51 recombinase	Homo sapiens	90-95