PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9032217-1 1997 Nafamostat mesilate (NM) is a synthetic protease inhibitor that is capable of inhibiting the various coagulation factors such as factor VIIa and thrombin. nafamostat 0-19 coagulation factor II Rattus norvegicus 145-153 24985053-0 2014 Nafamostat mesilate attenuates neuronal damage in a rat model of transient focal cerebral ischemia through thrombin inhibition. nafamostat 0-19 coagulation factor II Rattus norvegicus 107-115 24985053-5 2014 Thrombin expression and activity in the ipsilateral striatum were increased after ischemia, whereas the administration of nafamostat mesilate significantly inhibited thrombin expression and activity. nafamostat 122-141 coagulation factor II Rattus norvegicus 166-174 24985053-9 2014 These results suggest that nafamostat mesilate may have a potential therapeutic role for neuroprotection against focal cerebral ischemia through thrombin inhibition. nafamostat 27-46 coagulation factor II Rattus norvegicus 145-153 10066865-2 1999 We examined the effect of the synthetic serine protease inhibitor FUT-175 (developed as a potent inhibitor of thrombin and the complement system) on vascular lesions using balloon dilatation-induced neointimal formation in the carotid artery of rats. nafamostat 66-73 coagulation factor II Rattus norvegicus 110-118 6215361-1 1982 FUT-175 (6 amidino-2-naphthyl-4-guanidino benzoate-dimethanesulfonate), a new synthetic protease inhibitor, inhibits the enzyme activities of various proteases, such as Clr, C1 esterase, thrombin, kallikrein, plasmin and trypsin. nafamostat 0-7 coagulation factor II Rattus norvegicus 187-195 6215361-1 1982 FUT-175 (6 amidino-2-naphthyl-4-guanidino benzoate-dimethanesulfonate), a new synthetic protease inhibitor, inhibits the enzyme activities of various proteases, such as Clr, C1 esterase, thrombin, kallikrein, plasmin and trypsin. nafamostat 9-69 coagulation factor II Rattus norvegicus 187-195