PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20932608-1 2010 In this work, we report the synthesis and the antitubercular evaluation of 16 new mefloquine derivatives, formed from reactions between mefloquine and benzaldehydes, with the activity expressed as the minimum inhibitory concentration (MIC) in muM. Mefloquine 82-92 latexin Homo sapiens 243-246 28068604-5 2017 We found that quinoline derivatives 3a and 4 were the most potent compounds within this series, both with mean EC50 values of 0.8 muM, which represents a potency 5 times that of mefloquine. Mefloquine 178-188 latexin Homo sapiens 130-133