PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23760395-0 2013 Mefloquine exerts anticancer activity in prostate cancer cells via ROS-mediated modulation of Akt, ERK, JNK and AMPK signaling. Mefloquine 0-10 mitogen-activated protein kinase 8 Homo sapiens 104-107 23760395-11 2013 Moreover, we observed that MQ-mediated ROS simultaneously downregulated Akt phosphorylation and activated extracellular signal-regulated kinase (ERK), c-Jun N-terminal kinase (JNK) and adenosine monophosphate-activated protein kinase (AMPK) signaling in PC3 cells. Mefloquine 27-29 mitogen-activated protein kinase 8 Homo sapiens 151-174 23760395-11 2013 Moreover, we observed that MQ-mediated ROS simultaneously downregulated Akt phosphorylation and activated extracellular signal-regulated kinase (ERK), c-Jun N-terminal kinase (JNK) and adenosine monophosphate-activated protein kinase (AMPK) signaling in PC3 cells. Mefloquine 27-29 mitogen-activated protein kinase 8 Homo sapiens 176-179