PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31172009-6 2019 Results: In HT-29 cells, PTPN2 depletion resulted in enhanced mRNA expression of PTPN11 and PTPN23 and in parallel to upregulation of IL-18 mRNA upon treatment with TNF for 24 h. DSS treatment of PTPN2-deficient mice resulted in a strong induction of Ptpn23 mRNA in colon tissue in vivo. Dextran Sulfate 179-182 interleukin 18 Homo sapiens 134-139 30241336-7 2018 CST administration increased proliferation, viability, migration, TJ proteins, and p-STAT3 levels, and reduced IL-8 & IL-18 in LPS- & DSS-induced Caco2 cell epithelial injury, and the presence of STAT-3 inhibitor abolished the beneficial effect of CST. Dextran Sulfate 150-153 interleukin 18 Homo sapiens 126-131 30270565-2 2018 Our results show that the mRNA levels of IL-1beta, IL-18, NLRP3, ASC, and caspase-1 in the DSS+ZEA-treated group are lower than those in either the DSS or ZEA group, and the protein expression trends are similar. Dextran Sulfate 91-94 interleukin 18 Homo sapiens 51-56 12859727-9 2003 Immunohistochemical analysis revealed a significant increase of IL-18 production and CD11b+ macrophages but not CD4+ T cells in the inflamed mucosa in DSS-fed IL-18 Tg compared with DSS-fed WT mice. Dextran Sulfate 151-154 interleukin 18 Homo sapiens 64-69 12859727-9 2003 Immunohistochemical analysis revealed a significant increase of IL-18 production and CD11b+ macrophages but not CD4+ T cells in the inflamed mucosa in DSS-fed IL-18 Tg compared with DSS-fed WT mice. Dextran Sulfate 151-154 interleukin 18 Homo sapiens 159-164