PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9878126-11 1998 These results clearly demonstrate that IL-1 is involved in the development of DSS-induced colitis in mice and suggest that downregulation of IL-1 might be useful for the treatment of patients with ulcerative colitis. Dextran Sulfate 78-81 interleukin 1 complex Mus musculus 39-43 20936359-12 2011 RT-PCR demonstrated that both IL-1 and IL-10 expression were up-regulated in DSS-induced colitis while heparin lessened the up-regulation extent. Dextran Sulfate 77-80 interleukin 1 complex Mus musculus 30-34 9878126-11 1998 These results clearly demonstrate that IL-1 is involved in the development of DSS-induced colitis in mice and suggest that downregulation of IL-1 might be useful for the treatment of patients with ulcerative colitis. Dextran Sulfate 78-81 interleukin 1 complex Mus musculus 141-145 29666981-4 2018 In fact, this low-dose DSS priming apparently decreased the acute inflammation, as colitis scores along with IFNgamma, IL-1ss, and IL-4 were significantly decreased with the same tendency for IL-5, TNFalpha, and IL-2 on day 3 post-induction compared to control mice. Dextran Sulfate 23-26 interleukin 1 complex Mus musculus 119-123 1423638-3 1992 Low molecular weight (8000 Da) dextran sulfate also enhanced the T cell responses and synergized with IL-1, whereas, de-N-sulfated heparin was devoid of both of these activities. Dextran Sulfate 31-46 interleukin 1 complex Mus musculus 102-106 6205079-6 1984 In cultures of normal B cells activated with anti-IgM and dextran sulfate together, BGDF/IL 1 induced a proliferative response comparable with the sum of the responses to the factor and either stimulus alone. Dextran Sulfate 58-73 interleukin 1 complex Mus musculus 89-93 6205079-7 1984 These results suggest that anti-IgM and dextran sulfate activate distinct and independent B cell subpopulations, both of which are responsive to BGDF/IL 1. Dextran Sulfate 40-55 interleukin 1 complex Mus musculus 150-154 31035087-7 2019 The levels of TNF-alpha and IL-1ss were increased by DSS and dose-dependently inhibited by Saikosaponin A. Dextran Sulfate 53-56 interleukin 1 complex Mus musculus 28-32