PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12679326-10 2003 To determine the direct effect of MMP-1 on the myocardium, isolated adult rat myocytes were treated with active MMP-1, which caused injury and death of cultured myocytes, measured as lactate dehydrogenase release and trypan blue staining, in a dose- and time-dependent manner (P < 0.05). Trypan Blue 217-228 matrix metallopeptidase 1 Rattus norvegicus 112-117