PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3761757-2 1986 The IC50 values of tiapride, sulpiride and haloperidol were estimated as follows: 1440, 132 and 0.295 microM for D-1; 45.8, 8.8 and 0.004 microM for D-2; greater than 100, greater than 100 and 0.64 microM for D-3; 11.7, 2.88 and 0.0044 microM for D-4, respectively. Tiapride Hydrochloride 19-27 solute carrier family 3 member 1 Rattus norvegicus 149-152 3761757-3 1986 It is suggested that the affinity of tiapride is high to D-2 and D-4, but is not high to D-1 and D-3. Tiapride Hydrochloride 37-45 solute carrier family 3 member 1 Rattus norvegicus 57-68 3761757-5 1986 In the D-2 receptor assay, the IC50 values of tiapride and sulpiride were 1/22.7 and 1/19.1 of those in the presence of 100 mM NaCl, respectively, suggesting that benzamide drug binds to the D-2 subtype with higher affinity in the presence of Na+ than in the control. Tiapride Hydrochloride 46-54 solute carrier family 3 member 1 Rattus norvegicus 7-10 3761757-5 1986 In the D-2 receptor assay, the IC50 values of tiapride and sulpiride were 1/22.7 and 1/19.1 of those in the presence of 100 mM NaCl, respectively, suggesting that benzamide drug binds to the D-2 subtype with higher affinity in the presence of Na+ than in the control. Tiapride Hydrochloride 46-54 solute carrier family 3 member 1 Rattus norvegicus 191-194