PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27132804-3 2016 Combined treatment with Q+C was much more effective than either Q or C in inhibiting DNMT, causing global hypomethylation, restoring AR mRNA and protein levels and causing apoptosis via mitochondrial depolarization of PC3 and DU145. q+c 24-27 chromobox 8 Homo sapiens 218-221 27132804-5 2016 Bisulfite sequencing revealed high methylation of AR promoter CpG sites in AR-negative DU145 and PC3 cell lines that was significantly demethylated by Q+C treatment, which restored AR expression. q+c 151-154 chromobox 8 Homo sapiens 97-100