PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31414279-3 2019 Here, we developed such a system by conjugating gelatin-based nanogels with the nucleolin-targeted AS1411 aptamer and deoxynucleotide-substituted siRNA together (Apt-GS/siRNA) via a disulfide linker to achieve transient docking of siRNA. Disulfides 182-191 nucleolin Homo sapiens 80-89 23207101-6 2013 Both HMGB1 containing a disulfide bond between C23 and C45, which induces chemokine and cytokine release by activating TLR4, and HMGB1 terminally oxidized to contain a cysteine sulfonate are inactive in recruiting leukocytes. Disulfides 24-33 nucleolin Homo sapiens 47-50 23446148-4 2013 Firstly, the cytokine-stimulating activity of HMGB1 requires C23 and C45 to be in a disulfide linkage, at the same time that C106 must remain in its reduced form as a thiol. Disulfides 84-93 nucleolin Homo sapiens 61-64