PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30448513-6 2019 Here we show that Sac1undergoes reversible inactivation in mammalian cells when its catalytic Cys389 residue is oxidized by exogenous H2O2 to form an intramolecular disulfide with Cys392. Disulfides 165-174 SAC1 like phosphatidylinositide phosphatase Homo sapiens 18-22