PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7197282-2 1981 Treatment of CHO-K1 cells with CTAB or ethanol at concentrations that produce comparable increases of membrane fluidity produce to 2- to 3-fold increase of microsomal membrane cholesterol to phospholipid ratio and a 2- to 3-fold increase of the activity of the rate-limiting enzyme of cholesterol biosynthesis, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase. Cetrimonium 31-35 3-hydroxy-3-methylglutaryl-coenzyme A reductase Cricetulus griseus 311-368