PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26273599-5 2015 Markedly decreased levels of IL-17, retinoid-related orphan receptor C (RORc), and MMP-3 mRNA expression were also observed in IL-6-induced RASFs in the presence of T-614 or MTX compared with those in its absence. Methotrexate 174-177 RAR related orphan receptor C Homo sapiens 36-70 26273599-5 2015 Markedly decreased levels of IL-17, retinoid-related orphan receptor C (RORc), and MMP-3 mRNA expression were also observed in IL-6-induced RASFs in the presence of T-614 or MTX compared with those in its absence. Methotrexate 174-177 RAR related orphan receptor C Homo sapiens 72-76 30551543-5 2019 Concomitant treatment of CoQ10 & methotrexate caused improvement in histological picture of the lung and liver tissues, liver function and oxidative stress biomarkers, modulation of autophagy genes [mammalian target of rapamycin (m-TOR), Microtubule-associated proteins 1 A/1B light chain 3 (MAP1LC3B), and Sequestosome 1 ubiquitin-binding protein p62 (p62/SQSTM1)] with simultaneous reduction in High Mobility Group Protein B1 (HMGB1). Methotrexate 37-49 RAR related orphan receptor C Homo sapiens 236-239