PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28302487-7 2017 Here, we observed lncRNA TUG1 was associated to the MTX resistant in colorectal cancer cells. Methotrexate 52-55 taurine up-regulated 1 Homo sapiens 25-29 28302487-8 2017 Firstly, quantitative analysis indicated that TUG1 was significantly increased in tumors which were resistant to MTX treatment. Methotrexate 113-116 taurine up-regulated 1 Homo sapiens 46-50 28302487-9 2017 TUG1 knockdown re-sensitized the MTX resistance in colorectal cancer cells, which were MTX-resistant colorectal cell line. Methotrexate 33-36 taurine up-regulated 1 Homo sapiens 0-4 28302487-9 2017 TUG1 knockdown re-sensitized the MTX resistance in colorectal cancer cells, which were MTX-resistant colorectal cell line. Methotrexate 87-90 taurine up-regulated 1 Homo sapiens 0-4 28302487-12 2017 Taken together, our study suggests that lncRNA TUG1 mediates MTX resistance in colorectal cancer via miR-186/CPEB2 axis. Methotrexate 61-64 taurine up-regulated 1 Homo sapiens 47-51 28302487-0 2017 TUG1 mediates methotrexate resistance in colorectal cancer via miR-186/CPEB2 axis. Methotrexate 14-26 taurine up-regulated 1 Homo sapiens 0-4