PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33087502-8	2020	Furthermore, HSA also inhibited polyinosinic:polycytidylic acid- and lipopolysaccharide-induced interferon regulatory factor 3 phosphorylation and TIR domain-containing adapter-inducing interferon-beta-mediated responses, which are exclusive of endosomal TLR3 and TLR4 signaling, respectively.	Poly C	45-63	toll like receptor 4	Homo sapiens	264-268	
32454326-10	2020	We functionally challenged ovaries in vitro, by polyinosinic:polycytidylic acid (poly I:C) and LPS, known to activate TLR3 and TLR4, respectively, and found a tendency for increased IL-6 production, which was particular evident in the LPS-treated group.	Poly C	61-79	toll like receptor 4	Homo sapiens	127-131	
25345551-5	2015	RESULTS: Although flow cytometry and IHC revealed HBCs to be M2 (anti-inflammatory) macrophages, LPS and polyinosinic: polycytidylic acid [poly (I:C)] treatments markedly enhanced IL-6 secretion by HBCs, and expression of TLR-2, TLR-3, TLR-4, CD14, and MD-2 was the highest in HBCs.	Poly C	119-137	toll like receptor 4	Homo sapiens	236-241	
24035358-5	2013	It was found that microRNA-301a (miR-301a) was up-regulated by the ligands of TLR3 and TLR4, LPS and polyinosinic acid:polycytidylic acid poly(I:C).	Poly C	119-137	toll like receptor 4	Homo sapiens	87-91	
18725521-4	2008	In this study, we show that polyinosinic:polycytidylic acid (poly[I:C]) and lipopolysaccharide stimulation of macrophages induces pro-IL-1beta processing via a Toll/IL-1R domain-containing adaptor-inducing interferon-beta-dependent signaling pathway that is initiated by TLR3 and TLR4, respectively.	Poly C	41-59	toll like receptor 4	Homo sapiens	160-164	
18725521-4	2008	In this study, we show that polyinosinic:polycytidylic acid (poly[I:C]) and lipopolysaccharide stimulation of macrophages induces pro-IL-1beta processing via a Toll/IL-1R domain-containing adaptor-inducing interferon-beta-dependent signaling pathway that is initiated by TLR3 and TLR4, respectively.	Poly C	41-59	toll like receptor 4	Homo sapiens	280-284