PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29732121-4	2018	We previously established a bump-&-hole system for the BET bromodomains, pairing a leucine/alanine mutation with an ethyl-derived analogue of an established benzodiazepine scaffold.	Leucine	87-94	delta/notch like EGF repeat containing	Homo sapiens	59-62	
25323695-5	2014	We developed an ethyl derivative of an existing small-molecule inhibitor, I-BET/JQ1, and showed that it binds leucine/alanine mutant bromodomains with nanomolar affinity and achieves up to 540-fold selectivity relative to wild-type bromodomains.	Leucine	110-117	delta/notch like EGF repeat containing	Homo sapiens	76-79