PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2502402-3 1989 Mg2+ markedly enhanced the number of receptors with high affinity for the radiolabeled oligopeptide fMet-Leu-[3H]Phe. Leucine 105-108 mucin 7, secreted Homo sapiens 0-3 8639650-6 1996 The Ile-->Leu mutation seems to perturb the configuration of the metal-binding ligands at the active site so that the protein has virtually no affinity for Mg2+ yet it can still bind Mn2+ ions, though the latter only occurs when the protein is at the recognition site. Leucine 13-16 mucin 7, secreted Homo sapiens 159-162 8804604-5 1996 The difference in the P-region, causing the change in Mg2+ binding kinetics, was attributed to ShB delta (V443) and its analog Kv3.1(L401), because in both channels leucine at this position gave fast block, whereas valine gave slow block. Leucine 165-172 mucin 7, secreted Homo sapiens 54-57 2359406-1 1990 In the presence of Mg2+, pure glutamate dehydrogenase is more reactive with NADPH than with NADH and is markedly activated by elevations in the ADP/ATP ratio or the addition of leucine. Leucine 177-184 mucin 7, secreted Homo sapiens 19-22 2359406-3 1990 In the absence of the allosteric activators ADP, leucine, or succinyl-CoA, Mg2+ is an inhibitor and increases product inhibition by alpha-ketoglutarate in the forward reaction and substrate inhibition by alpha-ketoglutarate in the reverse reaction. Leucine 49-56 mucin 7, secreted Homo sapiens 75-78 2359406-5 1990 In the reverse reaction, ADP also converts Mg2+ from an inhibitor into an activator and leucine eliminates inhibition by Mg2+. Leucine 88-95 mucin 7, secreted Homo sapiens 43-46 2359406-5 1990 In the reverse reaction, ADP also converts Mg2+ from an inhibitor into an activator and leucine eliminates inhibition by Mg2+. Leucine 88-95 mucin 7, secreted Homo sapiens 121-124 2359406-7 1990 Leucine and its analog 2-aminobicyclo (2.2.1) heptane 2-carboxylic acid (BCH) have almost identical effects on both human and bovine glutamate dehydrogenase in both the presence and absence of Mg2+. Leucine 0-7 mucin 7, secreted Homo sapiens 193-196