PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2018041-4 1991 This nucleotide alteration results in the substitution of proline for the highly conserved leucine residue at position 285 of the ND1 protein. Leucine 91-98 mitochondrially encoded NADH dehydrogenase 1 Homo sapiens 130-133 22553750-5 2012 In addition, there were two secondary mutations in Pedigree 1: C3497T (Ala Val), and C3571T (Leu Phe) in the MT-ND1 gene, which have not been reported; and two secondary mutations occurred in Pedigree 2: A10398G (Thr Ala) in the MT-ND3 gene, and T14502C (Ile Val) in the MT-ND6 gene. Leucine 93-96 mitochondrially encoded NADH dehydrogenase 1 Homo sapiens 109-115 12112111-3 2002 This mutation replaces leucine with methionine in a conserved extramembrane loop of the ND1 gene and was absent in 514 normal controls and in 63 Leber"s hereditary optic neuropathy lineages harboring the primary mutations. Leucine 23-30 mitochondrially encoded NADH dehydrogenase 1 Homo sapiens 88-91