PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10655559-2 2000 METHODS: The resistance phenotype of doxorubicin-selected MCF-7(DXR) human breast adenocarcinoma cell line was characterized by cellular and nuclear daunorubicin efflux, P-gp and MRP expression and apoptosis induction. Doxorubicin 37-48 chromosome 19 open reading frame 48 Homo sapiens 179-182 8688320-5 1996 Furthermore, the expression of P-glycoprotein (P-gp) and multidrug resistance-related protein (MRP), which both can contribute to resistance to daunorubicin and doxorubicin, were immunohistochemically investigated. Doxorubicin 161-172 chromosome 19 open reading frame 48 Homo sapiens 95-98 8603335-10 1996 Also, analysis of RNA from parental-sensitive and DOX-resistant sublines by reverse transcriptase-polymerase chain reaction revealed: a) comparable expression of multidrug resistance related protein (MPR) in sensitive and resistant sublines; and b) overexpression of mdr-1 only in the DOX-resistant sublines. Doxorubicin 50-53 chromosome 19 open reading frame 48 Homo sapiens 162-198