PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29852388-9 2018 Moreover, cells with decreased Grp94 levels displayed an enhanced sensitivity of tumor cells to doxorubicin, a standard drug in the treatment of breast cancer. Doxorubicin 96-107 heat shock protein 90 beta family member 1 Homo sapiens 31-36 19205439-0 2008 Increased expression of GRP94 protein is associated with decreased sensitivity to adriamycin in ovarian carcinoma cell lines. Doxorubicin 82-92 heat shock protein 90 beta family member 1 Homo sapiens 24-29 19205439-6 2008 RESULTS: HO-8910PM cells, with the highest basal levels of GRP94, exhibited the lowest sensitivity to adriamycin. Doxorubicin 102-112 heat shock protein 90 beta family member 1 Homo sapiens 59-64 19205439-7 2008 In HO-8910PM cells, the sensitivity to adriamycin was increased when the GRP94 gene was disturbed by specific siRNA transfection. Doxorubicin 39-49 heat shock protein 90 beta family member 1 Homo sapiens 73-78 19205439-8 2008 CONCLUSIONS: High GRP94 expression might be one of the molecular mechanisms causing resistance to adriamycin, and therefore GRP94 siRNA maybe useful in tumor-specific gene therapy in ovarian cancer. Doxorubicin 98-108 heat shock protein 90 beta family member 1 Homo sapiens 18-23