PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15843167-0	2005	Doxorubicin induces EGF receptor-dependent downregulation of gap junctional intercellular communication in rat liver epithelial cells.	Doxorubicin	0-11	epidermal growth factor receptor	Rattus norvegicus	20-32	
23349960-10	2013	The phosphorylated EGFR/total EGFR ratio was reduced by 74+-7% in the Dox group and by 77+-4% in the Dox + Erl group.	Doxorubicin	70-73	epidermal growth factor receptor	Rattus norvegicus	19-23	
23349960-10	2013	The phosphorylated EGFR/total EGFR ratio was reduced by 74+-7% in the Dox group and by 77+-4% in the Dox + Erl group.	Doxorubicin	70-73	epidermal growth factor receptor	Rattus norvegicus	30-34	
23349960-10	2013	The phosphorylated EGFR/total EGFR ratio was reduced by 74+-7% in the Dox group and by 77+-4% in the Dox + Erl group.	Doxorubicin	101-104	epidermal growth factor receptor	Rattus norvegicus	19-23	
23349960-10	2013	The phosphorylated EGFR/total EGFR ratio was reduced by 74+-7% in the Dox group and by 77+-4% in the Dox + Erl group.	Doxorubicin	101-104	epidermal growth factor receptor	Rattus norvegicus	30-34	
22244893-6	2012	Doxorubicin induced p53 and p21 was suppressed by treatment with AG1478, an EGFR and ErbB4 kinase inhibitor, or suppression of ErbB4 expression with small interfering RNA.	Doxorubicin	0-11	epidermal growth factor receptor	Rattus norvegicus	76-80	
18371937-3	2008	Results have indicated that FaO cells show overactivation of the EGFR pathway, which induces basal growth (in the absence of serum) and protection from pro-apoptotic agents, such as doxorubicin, generating drug resistance.	Doxorubicin	182-193	epidermal growth factor receptor	Rattus norvegicus	65-69	
18371937-4	2008	Treatment of cells with the combination of doxorubicin and the tyrphostin 4-(3-chloroanilino)-6,7-dimethoxyquinazoline (AG1478, a potent and specific inhibitor of EGFR tyrosine kinase) potently inhibits autocrine growth and induces apoptosis.	Doxorubicin	43-54	epidermal growth factor receptor	Rattus norvegicus	163-167	
19622293-15	2009	CONCLUSION: The preventive and therapeutic effects of aloe gel on doxorubicin-induced extravasation injury are satisfactory, which may be in relation to the up-regulation of VEGF and EGFR.	Doxorubicin	66-77	epidermal growth factor receptor	Rattus norvegicus	183-187	
15843167-4	2005	Furthermore, activation of the epidermal growth factor (EGF) receptor by doxorubicin was responsible for ERK activation and the subsequent attenuation of GJC.	Doxorubicin	73-84	epidermal growth factor receptor	Rattus norvegicus	31-69	
15843167-5	2005	Inhibition of GJC, however, was not by direct phosphorylation of Cx43 by ERK-1/2, whereas menadione, a 1,4-naphthoquinone derivative that was previously demonstrated to activate the same EGF receptor-dependent pathway as doxorubicin, resulting in downregulation of GJC, caused strong phos-phorylation of Cx43 at serines 279 and 282.	Doxorubicin	221-232	epidermal growth factor receptor	Rattus norvegicus	187-199