PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19622293-15 2009 CONCLUSION: The preventive and therapeutic effects of aloe gel on doxorubicin-induced extravasation injury are satisfactory, which may be in relation to the up-regulation of VEGF and EGFR. Doxorubicin 66-77 epidermal growth factor receptor Rattus norvegicus 183-187 23349960-10 2013 The phosphorylated EGFR/total EGFR ratio was reduced by 74+-7% in the Dox group and by 77+-4% in the Dox + Erl group. Doxorubicin 70-73 epidermal growth factor receptor Rattus norvegicus 19-23 23349960-10 2013 The phosphorylated EGFR/total EGFR ratio was reduced by 74+-7% in the Dox group and by 77+-4% in the Dox + Erl group. Doxorubicin 70-73 epidermal growth factor receptor Rattus norvegicus 30-34 23349960-10 2013 The phosphorylated EGFR/total EGFR ratio was reduced by 74+-7% in the Dox group and by 77+-4% in the Dox + Erl group. Doxorubicin 101-104 epidermal growth factor receptor Rattus norvegicus 19-23 23349960-10 2013 The phosphorylated EGFR/total EGFR ratio was reduced by 74+-7% in the Dox group and by 77+-4% in the Dox + Erl group. Doxorubicin 101-104 epidermal growth factor receptor Rattus norvegicus 30-34 22244893-6 2012 Doxorubicin induced p53 and p21 was suppressed by treatment with AG1478, an EGFR and ErbB4 kinase inhibitor, or suppression of ErbB4 expression with small interfering RNA. Doxorubicin 0-11 epidermal growth factor receptor Rattus norvegicus 76-80 15843167-0 2005 Doxorubicin induces EGF receptor-dependent downregulation of gap junctional intercellular communication in rat liver epithelial cells. Doxorubicin 0-11 epidermal growth factor receptor Rattus norvegicus 20-32 18371937-3 2008 Results have indicated that FaO cells show overactivation of the EGFR pathway, which induces basal growth (in the absence of serum) and protection from pro-apoptotic agents, such as doxorubicin, generating drug resistance. Doxorubicin 182-193 epidermal growth factor receptor Rattus norvegicus 65-69 18371937-4 2008 Treatment of cells with the combination of doxorubicin and the tyrphostin 4-(3-chloroanilino)-6,7-dimethoxyquinazoline (AG1478, a potent and specific inhibitor of EGFR tyrosine kinase) potently inhibits autocrine growth and induces apoptosis. Doxorubicin 43-54 epidermal growth factor receptor Rattus norvegicus 163-167 15843167-4 2005 Furthermore, activation of the epidermal growth factor (EGF) receptor by doxorubicin was responsible for ERK activation and the subsequent attenuation of GJC. Doxorubicin 73-84 epidermal growth factor receptor Rattus norvegicus 31-69 15843167-5 2005 Inhibition of GJC, however, was not by direct phosphorylation of Cx43 by ERK-1/2, whereas menadione, a 1,4-naphthoquinone derivative that was previously demonstrated to activate the same EGF receptor-dependent pathway as doxorubicin, resulting in downregulation of GJC, caused strong phos-phorylation of Cx43 at serines 279 and 282. Doxorubicin 221-232 epidermal growth factor receptor Rattus norvegicus 187-199