PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28654865-5 2017 Of the two phosphatidylcholine-specific PLD enzymes, only PLD1, but not PLD2, mRNA was down-regulated by doxorubicin treatment. Doxorubicin 105-116 phospholipase D1 Homo sapiens 58-62 28654865-8 2017 PLD1 and ChKalpha protein levels decreased following doxorubicin treatment in a concentration dependent manner. Doxorubicin 53-64 phospholipase D1 Homo sapiens 0-4 28654865-9 2017 Treatment with the PLD1 specific inhibitor VU0155069 sensitized MCF7 and MDA-MB-231 breast cancer cells to doxorubicin-induced cytotoxicity. Doxorubicin 107-118 phospholipase D1 Homo sapiens 19-23 28654865-12 2017 Doxorubicin induced GPC increase and PC decrease are caused by reductions in PLD1, GDPD6, and ChKalpha mRNA and protein expression. Doxorubicin 0-11 phospholipase D1 Homo sapiens 77-81