PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21851097-2	2011	Here we used novel strategies to target microsomal glutathione transferase 1 (MGST1) and glutathione transferase pi (GSTP) that are often overexpressed in tumors and confer resistance against a number of cytostatic drugs, including cisplatin and doxorubicin (DOX).	Doxorubicin	246-257	microsomal glutathione S-transferase 1	Homo sapiens	78-83	
24210875-3	2014	We demonstrate in this work that polyester-based hyperbranched dendritic-linear (HBDL)-based NPs carrying doxorubicin (Dox) can effectively overcome microsomal glutathione transferase 1 (MGST1)-mediated drug resistance in breast cancer cells.	Doxorubicin	106-117	microsomal glutathione S-transferase 1	Homo sapiens	187-192	
24210875-3	2014	We demonstrate in this work that polyester-based hyperbranched dendritic-linear (HBDL)-based NPs carrying doxorubicin (Dox) can effectively overcome microsomal glutathione transferase 1 (MGST1)-mediated drug resistance in breast cancer cells.	Doxorubicin	119-122	microsomal glutathione S-transferase 1	Homo sapiens	187-192	
24210875-7	2014	Moreover, we found that Dox-HBDL significantly decreased the expression of MGST1 and enhanced mitochondria-mediated apoptotic cell death compared to free Dox.	Doxorubicin	24-27	microsomal glutathione S-transferase 1	Homo sapiens	75-80	
21851097-2	2011	Here we used novel strategies to target microsomal glutathione transferase 1 (MGST1) and glutathione transferase pi (GSTP) that are often overexpressed in tumors and confer resistance against a number of cytostatic drugs, including cisplatin and doxorubicin (DOX).	Doxorubicin	259-262	microsomal glutathione S-transferase 1	Homo sapiens	78-83	
21851097-6	2011	Here we synthesized two derivatives of DOX, 2,4-dinitrobenzenesulfonyl doxorubicin (DNS-DOX) and 4-mononitrobenzenesulfonyl doxorubicin (MNS-DOX) and showed that they are substrates for MGST1 and GSTP (releasing DOX).	Doxorubicin	39-42	microsomal glutathione S-transferase 1	Homo sapiens	186-191	
21851097-7	2011	MGST1 overexpressing cells are resistant to DOX.	Doxorubicin	44-47	microsomal glutathione S-transferase 1	Homo sapiens	0-5	
21851097-10	2011	It would appear that, by controlling the reactivity of the prodrug, and thereby the DOX release rate, selective toxicity to MGST1 overexpressing cells can be achieved.	Doxorubicin	84-87	microsomal glutathione S-transferase 1	Homo sapiens	124-129	
19307502-10	2009	MGST1 expression was associated with doxorubicin chemosensitivity.	Doxorubicin	37-48	microsomal glutathione S-transferase 1	Homo sapiens	0-5